CLINICAL OUTCOMES OF PROLONGED INFUSION (EXTENDED INFUSION OR CONTINUOUS INFUSION) VERSUS INTERMITTENT BOLUS OF MEROPENEM IN SEVERE INFECTION: A META-ANALYSIS.

BACKGROUND:Meropenem exhibits time-dependent antimicrobial activity and prolonged infusion (PI) (extended infusion or continuous infusion, EI or CI) of meropenem can better achieve pharmacodynamics target when comparing with intermittent bolus (IB).However, the clinical outcomes between two groups remain inconclusive.OBJECTIVE:To evaluate current p

Background Restless Legs Syndrome (RLS) is a neurological sensorimotor disorder that occurs in the evening and night, thereby impacting quality of sleep in sufferers.The pathophysiology of RLS is poorly understood but inflammation has been proposed as possibly being involved.The neutrophil-to-lymphocyte ratio (NLR) can be used as an inflammation ma

The value of surface electromyograms (EMGs) lies in their potential to non-invasively probe the neuromuscular system.Whether muscle excitation may be accurately inferred from bipolar EMGs depends on how much the detected signal is both sensitive and specific to the excitation of the target muscle.While both are known to be a function of the inter-e

Vehicle detection (VD) on remote sensing (RS) images has gained impressive achievements these years, mainly thanks to the development of popular learning-based object detection architectures [e.g., faster R-convolutional neural network (CNN), YOLO series, etc.].However, for RS images, mutiscale VD with tiny size still remains challenging.Particular